Table 1. Baseline characteristics of the included patients in the original groups.
| Variables | RCA-CVVH (n = 41) | No-anticoagulation-CVVH (n = 62) | P-value |
|---|---|---|---|
| Gender, male, n (%) | 22 (53.7) | 42 (67.7) | 0.149 |
| Age, years | 52.49 ± 15.62 | 47.13 ± 14.08 | 0.073 |
| APACHE II | 17.12 ± 4.30 | 16.00 ± 5.73 | 0.286 |
| SOFA | 11.44 ± 4.04 | 11.65 ± 4.35 | 0.809 |
| Child-Pugh score | 8.51 ± 1.31 | 9.37 ± 1.26 | 0.001 |
| MELD score | 29.78 ± 6.93 | 34.74 ± 11.32 | 0.014 |
| Bilirubin, μmol/L | 67.57 ± 26.10 | 184.95 ± 138.38 | <0.001 |
| PLT, 109/L | 98.8 ± 60.65 | 90.19 ± 70.97 | 0.525 |
| FIB, g/L | 2.29 ± 1.36 | 1.67 ± 1.16 | 0.050 |
| APTT, s | 45.86 ± 29.52 | 66.34 ± 36.56 | 0.006 |
| PTA, % | 30.67 ± 17.41 | 28.84 ± 16.21 | 0.588 |
| INR | 2.35 ± 1.27 | 2.67 ± 1.48 | 0.261 |
| BUN, mmol/L | 23.57 ± 13.57 | 18.44 ± 11.85 | 0.045 |
| Serum Creatinine, μmol/L | 297.83 ± 141.28 | 324.56 ± 251.37 | 0.537 |
| Liver failure, acute, n (%) | 39 (95.1) | 51 (82.3) | 0.054 |
| AKI stage, 1/2/3, n (%) | 0(0)/13(31.7)/28(68.3) | 5(8.1)/11(17.7)/43(69.4) | 0.017 |
| Hypernatremia, yes, n (%) | 4 (9.8) | 3 (4.8) | 0.432 |
| Hyperkalemia, yes, n (%) | 15 (36.6) | 17 (27.4) | 0.325 |
| Fluid overload, yes, n (%) | 12 (29.3) | 10 (16.1) | 0.111 |
| Sepsis, yes, n (%) | 4 (9.8) | 7 (11.3) | 1.000 |
RCA, Regional citrate anticoagulation; CVVH, continuous venovenous hemofiltration; PLT, platelet counts; FIB, fibrinogen; APTT, activated partial thromboplastin time; PTA, prothrombin time activity; INR, international normalized ratio; BUN, blood urea nitrogen; AKI, Acute kidney injury. Unless indicated otherwise, data are presented as the mean ± standard deviation (SD).