Table 2. Predictors of filter failure in CVVH patients with liver failure and increased bleeding risk.

		Univariate Cox regression			Multivariate Cox regression			Multivariate Cox regression adjusted the important clinical parameters
		HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value
Anticoagulation strategy (RAC/no-anticoagulation)		0.48	0.295–0.779	0.003	0.392	0.222–0.695	0.001	0.459	0.259–0.815	0.008
Filter Type (M100 / AV600)		0.578	0.180–1.856	0.357	-	-	-	109626.395	0.000	0.974
Vascular access		0.325	0.079–1.337	0.119	-	-	-	0.384	0.092–1.604	0.19
PLT		0.994	0.990–0.999	0.008	0.997	0.993–1.001	0.182	0.996	0.992–1.001	0.99
APTT		1.005	1.000–1.010	0.045	1.007	1.002–1.012	0.004	1.008	1.001–1.015	0.018
INR		1.001	0.999–1.003	0.284	-	-	-	1.010	0.822–1.242	0.922
HBG		1.003	0.996–1.010	0.34	-	-	-	1.009	1.001–1.018	0.036

RCA, Regional citrate anticoagulation; CVVH, continuous venovenous hemofiltration; PLT, platelet; APTT, activated partial thromboplastin time; INR, international normalized ratio; HBG, hemoglobin.