Table 4. Baseline characteristics of the included patients in the matched groups.
Variables | RCA-CVVH (n = 26) | No-anticoagulation-CVVH (n = 26) | P-value |
---|---|---|---|
Gender, male, n (%) | 13 (50) | 16 (61.5) | 0.402 |
Age, years | 51.19 ± 15.92 | 46.88 ± 14.61 | 0.314 |
APACHE II | 17.31 ± 4.59 | 16.46 ± 4.90 | 0.524 |
SOFA | 12.58 ± 4.02 | 11.38 ± 5.01 | 0.349 |
Child-Pugh score | 8.58 ± 1.24 | 8.92 ± 1.02 | 0.833 |
MELD score | 31.85 ± 7.16 | 32.23 ± 5.89 | 0.276 |
Bilirubin, μmol/L | 78.61 ± 25.94 | 88.82 ± 50.47 | 0.363 |
PTA, % | 27.67 ± 16.32 | 25.64 ± 13.32 | 0.626 |
INR | 2.46 ± 1.52 | 2.66 ± 1.17 | 0.604 |
Serum Creatinine, μmol/L | 350.08 ± 150.87 | 313.27 ± 149.71 | 0.381 |
Liver failure, acute, n (%) | 26 (100) | 26 (100) | 1.000 |
AKI stage, 1/2/3, n (%) | 0(0)/5(19.2)/21(80.8) | 2(7.7)/5(19.2)/19(73.1) | 0.238 |
Hypernatremia, yes, n (%) | 1 (3.8) | 0 (0) | 1.000 |
Hyperkalemia, yes, n (%) | 10 (38.5) | 6 (23.1) | 0.229 |
Fluid overload, yes, n (%) | 8 (30.8) | 4 (15.4) | 0.188 |
Sepsis, yes, n (%) | 4 (15.4) | 3 (11.5) | 1.000 |
RCA, Regional citrate anticoagulation; CVVH, continuous venovenous hemofiltration; PTA, prothrombin time activity; INR, international normalized ratio; AKI, Acute kidney injury. Unless indicated otherwise, data are presented as the mean ± standard deviation (SD)