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. 2020 May 5;15(5):e0225290. doi: 10.1371/journal.pone.0225290

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© 2020 Shi et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — A: Detection of cell viability of original cell line (TE-1) and drug-resistant cell line (TE1/DDP) under 2.5 μM DDP conditions. B: Apoptosis detection in original cell line (TE-1) and drug-resistant cell line (TE1/DDP) under 2.5 μM DDP. C: Scanning electron microscopy to identify exosomes. D: Western blot analysis of good exosome membrane protein marker CD63. E: CCK-8 detects cell viability showing that drug-resistant exosomes (TE1/DDP/exo) promote DDP resistance in TE1 cells.