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. 2020 May 5;15(5):e0225290. doi: 10.1371/journal.pone.0225290

Fig 4. In vitro experiments demonstrate that both drug-resistant exosomes and miRNA193 increase the sensitivity of sensitive cells to cisplatin.

Fig 4

A, B: nude mice and postoperative tumor photos. C: Comparison of tumor size in different groups of nude mice. D: Tumor growth curves in different groups and different locations. The group situation is shown in the upper left corner of Fig A. For Group A and Group D, TE-1/DDP was injected into the left underarm of nude mice (L, the corresponding tumor in Fig B was the tumor on the top of each group), and TE-1 was inoculated in the right underarm (R, the corresponding tumor in Fig B was the tumor on the bottom of each group). For Group B and Group E, TE-1/miR193 mimic was inoculated into the left underarm of nude mice, and TE-1 was inoculated in the right underarm. For Group C and Group F, TE-1 was inoculated in both underarms of nude mice. In the Fig C D, the mark “A-L” means the tumor in the left underarm of nude mice in group A, which was injected TE-1/DDP.