Table 2.
Blood, urine, and C-reactive protein (CRP) tests.
| Group | Before the surgery |
After the surgery |
5 hours after surgery |
20 hours after surgery |
|
|---|---|---|---|---|---|
| aPTT (sec) | Diclofenac | 30.2±4.3 | 31.1±3.6 | 36.3±8.0 | 31.3±3.9† |
| Control | 31.6± 6.0 | 32.2±4.6 | 37.2±8.7 | 32.6±4.4† | |
| PT (units) | Diclofenac | 0.90±0.12 | 0.67±0.08 | 0.72±0.09 | 0.85±0.09† |
| Control | 0.89±0.11 | 0.65±0.09 | 0.70±0.07 | 0.82±0.09† | |
| TT (sec) | Diclofenac | 20.09±1.88 | 26.15±7.75* | 49.87±37.53 | 21.03±3.37† |
| Control | 20.21±2.79 | 23.00±3.38 | 43.79±30.14 | 19.76±3.63† | |
| Fibrinogen (g/l) | Diclofenac | 4.41±1,33 | 2.94±0.80 | 3.05±0.88 | 3.87±0.82† |
| Control | 4.22±1,06 | 2.79±0.76 | 3.05±0.77 | 3.91±0.79† | |
| Platelet count (109/L) | Diclofenac | 240±64 | 180±58 | 191±61 | 186±54† |
| Control | 237±114 | 169±92 | 182±85 | 182±78† | |
| Platelet aggregation Adenosine diphosphate (%) | Diclofenac | 73±16 | 75±18 | 73±19 | 76±18 |
| Control | 70±20 | 78±22 | 79±20 | 80±11 | |
| Epinephrine (%) | Diclofenac | 44±25 | 38±23 | 33±20 | 51±24† |
| Control | 43±29 | 36±26 | 42±32 | 61±27† | |
| Arachidonic acid (%) | Diclofenac | 27±32 | 34±31 | 29±34 | 35±31 |
| Control | 29±34 | 35±33 | 42±35 | 49±32 | |
| Collagen (%) | Diclofenac | 73±17 | 70±24 | 60±25 | 74±19 |
| Control | 66±19 | 70±31 | 67±27 | 71±20 | |
| Urea (mmol/L) | Diclofenac | 6.3±1.6 | 5.6±1.1 | 6.0±1.8 | |
| Control | 6.6±2.0 | 6.2±1.5 | 6.5±2.0 | ||
| Creatinine (µmol/L) | Diclofenac | 83±16 | 75±14 | 84±21 | |
| Control | 87±22 | 82±18 | 90±27 | ||
| Lactate (mmol/L) | Diclofenac | 1.9±0.7 | 2.8±1.7 | 1.9±0.5 | |
| Control | 2.3±0.9 | 3.6±2.0 | 2.2±0.8 | ||
| Troponin (µmol/L) | Diclofenac | 2.6±2.1 | 6.8±6.8 | 3.3±3.1 | |
| Control | 2.9±1.7 | 5.3±2.6 | 3.6±2.8 | ||
| CRP (mg/L) | Diclofenac | 6±4 | 4±2 | 33±15* | |
| Control | 7±7 | 9±22 | 46±22 | ||
Mean values ± standard deviation
statistically significant difference (P<0.05) between groups (analysis of variance for repeated measurements)
statistically significant difference (P<0.05) within the group (analysis of variance for repeated measurements)
aPTT=activated partial thromboplastin time; PT=prothrombin time; TT=thrombin time