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. 2020 Mar-Apr;35(2):160–168. doi: 10.21470/1678-9741-2019-0283

Table 2.

Blood, urine, and C-reactive protein (CRP) tests.

Group Before the
surgery
After the
surgery
5 hours after
surgery
20 hours after
surgery
aPTT (sec) Diclofenac 30.2±4.3 31.1±3.6 36.3±8.0 31.3±3.9
Control 31.6± 6.0 32.2±4.6 37.2±8.7 32.6±4.4
PT (units) Diclofenac 0.90±0.12 0.67±0.08 0.72±0.09 0.85±0.09
Control 0.89±0.11 0.65±0.09 0.70±0.07 0.82±0.09
TT (sec) Diclofenac 20.09±1.88 26.15±7.75* 49.87±37.53 21.03±3.37
Control 20.21±2.79 23.00±3.38 43.79±30.14 19.76±3.63
Fibrinogen (g/l) Diclofenac 4.41±1,33 2.94±0.80 3.05±0.88 3.87±0.82
Control 4.22±1,06 2.79±0.76 3.05±0.77 3.91±0.79
Platelet count (109/L) Diclofenac 240±64 180±58 191±61 186±54
Control 237±114 169±92 182±85 182±78
Platelet aggregation Adenosine diphosphate (%) Diclofenac 73±16 75±18 73±19 76±18
Control 70±20 78±22 79±20 80±11
Epinephrine (%) Diclofenac 44±25 38±23 33±20 51±24
Control 43±29 36±26 42±32 61±27
Arachidonic acid (%) Diclofenac 27±32 34±31 29±34 35±31
Control 29±34 35±33 42±35 49±32
Collagen (%) Diclofenac 73±17 70±24 60±25 74±19
Control 66±19 70±31 67±27 71±20
Urea (mmol/L) Diclofenac 6.3±1.6 5.6±1.1   6.0±1.8
Control 6.6±2.0 6.2±1.5   6.5±2.0
Creatinine (µmol/L) Diclofenac 83±16 75±14   84±21
Control 87±22 82±18   90±27
Lactate (mmol/L) Diclofenac 1.9±0.7 2.8±1.7   1.9±0.5
Control 2.3±0.9 3.6±2.0   2.2±0.8
Troponin (µmol/L) Diclofenac   2.6±2.1 6.8±6.8 3.3±3.1
Control   2.9±1.7 5.3±2.6 3.6±2.8
CRP (mg/L) Diclofenac 6±4 4±2   33±15*
Control 7±7 9±22   46±22

Mean values ± standard deviation

*

statistically significant difference (P<0.05) between groups (analysis of variance for repeated measurements)

statistically significant difference (P<0.05) within the group (analysis of variance for repeated measurements)

aPTT=activated partial thromboplastin time; PT=prothrombin time; TT=thrombin time