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. 2020 Apr 12;10(4):e035168. doi: 10.1136/bmjopen-2019-035168

Table 5.

Descriptors in the study design/masking field in the analysed registered trial protocols on ClinicalTrials.gov (N=157)

Blinding terminology used in analysed registered clinical trial protocols N
Quadruple (participant, care provider, investigator, outcomes assessor) 39
None (open label) 22
Single (participant) 15
Double (participant, investigator) 14
Double (participant, outcomes assessor) 14
Triple (participant, investigator, outcomes assessor) 13
Triple (participant, care provider, investigator) 12
Single (outcomes assessor) 8
Single (investigator) 6
Double (participant, care provider) 5
Triple (participant, care provider, outcomes assessor) 4
Study described as observational, without information about blinding/masking 2
Double (investigator, outcomes assessor) 1
Masking: triple (participant, care provider, investigator) 1
Single (care provider) 1