Table 2.
Frequency of different genotypes and alleles of the Foxp3 rs3761549 SNP in HT patients compared to healthy subjects
| rs3761549 SNP | ||||
|---|---|---|---|---|
| Genotype/allele | Patients | Controls | OR (95% CI) | P-value |
| CC | 100 (77.5) | 103 (81.1) | 1.00 (reference) | |
| CT | 22 (17.1) | 15 (11.8) | 0.8 (0.4-1.4) | 0.4 |
| TT | 7 (5.4) | 9 (7.1) | 1.62 (0.8-3.2) | 0.2 |
| C | 223 (86.8) | 221 (87) | 1.00 (reference) | |
| T | 34 (13.2) | 33 (13.0) | 1.02 (0.6-1.7) | 0.9 |
| CC (D) | 100 (77.5) | 103 (81.1) | 1.00 (reference) | |
| CT+TT | 29 (22.5) | 24 (18.9) | 0.6 (0.2-1.8) | 0.4 |
| TT (R) | 6 (4.6) | 9 (7.1) | 1.00 (reference) | |
| CC+CT | 123 (95.4) | 118 (92.9) | 1.62 (0.8-3.2) | 0.2 |
Data are presented as number (%).R, recessive; D, dominant, Hashimoto's thyroiditis: HT; Forkhead box P3: Foxp3; SNP: Single nucleotide polymorphism; OR: Odds ratio; CI: Confidence interval.