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. 2020 May 6;65(7):569–575. doi: 10.1038/s10038-020-0771-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Summary of SARS-CoV-2-dreived T cell epitopes. a Distribution of SARS-CoV-2-dreived HLA-class I and II epitopes with the high binding affinity derived from the SARS-CoV-2 protein sequence (SARS-CoV-2_Wuhan-Hu-1) [1]. Red bars represent strong binding affinity epitopes with <0.5% rank and 2% rank, to HLA class I and class II, respectively, for each HLA molecule. b Genomic organization of SARS-CoV-2. ORF, open reading frame, S spike, E envelope, M membrane, N nucleocapsid proteins. c Similarity plot based on the full-length genome sequence of SARS-CoV-2. Genome sequences of SARS-CoV-2_WIV02 (accession number MN996527), SARS-CoV_GZ02 (AY390556), and Bat-CoV_RaTG13 (MN996532) were compared with SARS-CoV-2_Wuhan-Hu-1 (MN908947)