Table 1.
Patient Characteristics
| Netherlands | Spain | UK | Finland | |||||
|---|---|---|---|---|---|---|---|---|
| Pre-DHPC N = 4,418 n (%) |
Post-DHPC N = 3,124 n (%) |
Pre-DHPC N = 12,584 n (%) |
Post-DHPC N = 7,124 n (%) |
Pre-DHPC N = 9,951 n (%) |
Post-DHPC N = 7,497 n (%) |
Pre-DHPC N = 3,412 n (%) |
Post-DHPC N = 3,968 n (%) |
|
| Age, mean ± SD | 66 ± 15 | 66 ± 15 | 69 ± 13 | 69 ± 13 | 65 ± 15 | 67 ± 15 | 71 ± 14 | 70 ± 14 |
| Gender, Male | 1,912 (43) | 1,420 (45) | 5,498 (44) | 3,168 (44) | 3,071 (31) | 2,625 (35) | 1,129 (33) | 1,343 (34) |
| Hypertension status | ||||||||
| Severe uncontrolled hypertension | 27 (0.6) | 8 (0.3) | 42 (0.3) | 30 (0.4) | 46 (0.5) | 33 (0.4) | 44 (1.3) | 74 (1.9) |
| Non-severe uncontrolled hypertension | 700 (16) | 431 (14) | 1,578 (13) | 811 (11) | 1,488 (15) | 1,173 (16) | 442 (13) | 534 (13) |
| Controlled hypertension | 545 (12) | 423 (14) | 3,477 (28) | 1,921 (27) | 2,235 (22) | 1,762 (24) | 333 (10) | 388 (10) |
| Normal blood pressure | 1,836 (42) | 1,274 (41) | 4,623 (37) | 2,686 (38) | 4,202 (42) | 2,971 (40) | 1,190 (35) | 1,325 (33) |
| Unconfirmed hypertension status | 1,310 (30) | 988 (32) | 2,864 (23) | 1,676 (24) | 1,980 (20) | 1,558 (21) | 1,403 (41) | 1,647 (42) |
| Comorbid conditions | ||||||||
| Acute myocardial infarction (MI)a | 90 (2) | 76 (2) | 314 (2) | 179 (3) | 63 (1) | 87 (1) | 143 (4) | 158 (4) |
| Ischemic heart diseases (excl. MI)a | 208 (5) | 158 (5) | 911 (7) | 506 (7) | 320 (3) | 360 (5) | 517 (15) | 647 (16) |
| Cardiac arrhythmiasa | 232 (5) | 181 (6) | 1,093 (9) | 694 (10) | 281 (3) | 384 (5) | 673 (20) | 842 (21) |
| Congestive heart failurea | 104 (2) | 75 (2) | 414 (3) | 249 (3) | 118 (1) | 139 (2) | 212 (6) | 258 (7) |
| Cerebrovascular eventsa | 267 (6) | 204 (7) | 1,209 (10) | 699 (10) | 489 (5) | 542 (7) | 558 (16) | 587 (15) |
| Peripheral artery disease (PAD)a | 170 (4) | 124 (4) | 552 (4) | 330 (5) | 80 (1) | 87 (1) | 164 (5) | 196 (5) |
| Chronic kidney disease (CKD)a | 230 (5) | 209 (7) | 965 (8) | 615 (9) | 682 (7) | 666 (9) | 79 (2) | 101 (3) |
| Diabetesab | 598 (14) | 409 (13) | 2,692 (21) | 1,483 (21) | 1,486 (15) | 1,276 (17) | 566 (17) | 770 (19) |
| Hyperlipidaemiaab | 1,491 (34) | 1,054 (34) | 5,413 (43) | 2,897 (41) | 3,632 (36) | 2,931 (39) | 1,099 (32) | 1,495 (38) |
| Chronic respiratory diseaseab | 664 (15) | 490 (16) | 1,867 (15) | 989 (14) | 2,173 (22) | 1,557 (21) | 422 (12) | 564 (14) |
Notes: aAny time before starting mirabegron; bbased on treatment or diagnosis.