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. 2020 May 1;13:3689–3701. doi: 10.2147/OTT.S238338

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© 2020 Yin et al.

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The depletion of circ_0007142 impeded cell proliferation, colony formation, migration, and invasion in HT-29 and HCT-116 cells. (A–F) The HT-29 and HCT-116 cells were transfected with si-NC or si-circ_0007142. (A) The level of circ_0007142 was tested by qRT-PCR. (B) Both mRNA level and protein level of DOCK1 were measured by qRT-PCR and Western blot assay. (C) The cell viability was monitored via MTT assay. (D) The colony-forming ability was examined by colony formation assay. (E,F) The migrated and invaded abilities were assessed by Transwell assay. *P<0.05, **P<0.01.