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. 2020 May 1;15:3099–3120. doi: 10.2147/IJN.S210320

Table 1.

Different Types of Cur-Loaded Polymeric Micelles

Types of Micelles Composition Preparation Methods Major Outcome References
Normal micelles MPEG-PCL Solid dispersion method Improved water solubility
Inhibition of breast tumor growth and spontaneous pulmonary metastasis
[51]
EGFR-targeted micelles PLGA-PEG
GE11 peptides
Emulsification solvent evaporation method Increased intracellular uptake
Prolonged circulation
A reduction in primary tumor burden
[58]
FR-targeted micelles Folate-PEG3000-PLA2000
mPEG2000-PLA2000
Thin film-hydration method Increased intracellular uptake
Sustained drug release
Improved solubility
Cancer targeting
Enhanced anti-cancer activity
[13]
pH-sensitive micelles TPGS-PAE Solvent evaporation method Low polydispersity
High encapsulation efficiency
Enhanced release in the acidic environment
Improved pro-apoptotic and antiangiogenic
activities
[60]
Redox-sensitive micelles C16-SS-CS-mPEG Dialysis method Controlled drug release
Enhanced antitumor and anti-inflammation efficacy
[61]