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. 2020 May 1;15:3099–3120. doi: 10.2147/IJN.S210320

Table 2.

Preparation Methods of Cur-Loaded Nanocrystals

Types of Preparation Methods Preparation Methods Particle Size (nm) Stabilizers References
Top-down High-pressure homogenization method 500–800 PVA, PVP, TPGS, sodium carboxyl methyl cellulose (Na-CMC) or sodium dodecyl sulfate (SDS) [163]
Grinding method 250 Hydroxypropyl cellulose
SL (HPC-SL) and SDS
[164]
Grinding and high-pressure homogenization method 181 Stabilizer solution [165]
Bottom-up Precipitation method 104 or 135 Sodium lauryl sulfate or poloxamer 188 [166]
Thin-film dispersion method 161.9 Pluronic F127 [167]