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. 2020 May 1;13:3677–3687. doi: 10.2147/OTT.S242462

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© 2020 Li et al.

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SCAMP3 is upregulated in glioma tissues. (A) RT-qPCR results demonstrated that SCAMP3-mRNA is higher in gliomas compared with normal brain tissues. (B) Representative IHC images of SCAMP3 staining in gliomas and brain tissues. Magnification: 400×. (C) The IHC score of SCAMP3 was significantly higher in gliomas than that in nontumorous tissues. (D) ROC curve was plotted to identify the cutoff value to divide patients into high-SCAMP3 group and low-SCAMP3 group based on the IHC scores. The area under curve is 0.650 and IHC score=5.0 was identified as the cutoff score. **P<0.01 by Student’s t-test, ***P<0.001 by Student’s t-test.