Table 1.

Reaction conditions for the direct decarboxylative alkylation (DDA) of anilines.^[a]

Entry	Change from optimal conditions	Yield, %[b]
1	No change	99 (97[c])
2	No light	0
3	No A1	0
4	No Cu(hfac)2	0
5	No DTBP	7
6	A2 instead of A1	86
7	Cu(acac)2 instead of Cu(hfac)2	38
8	PhCF3 instead of EtOAc	78
9	PhCH3 instead of EtOAc	76
10	420 nm instead of 400 nm LED	86
11	Under air	94

^[a]Reaction conditions: aniline (0.3 mmol), carboxylic acid (0.75 mmol), A1 (10 mol%), Cu(hfac)₂ (10 mol%), DTBP (0.6 mmol), EtOAc (4.5 mL), LED (400 nm), 12 h.

^[b]Determined by ¹H NMR with 1,4-dimethoxybenzene as an internal standard.

^[c]Isolated yield.