Table 5.
Sensitivity and specificity of nine test for detection of stroke in SLE patients.
TEST | HPPNA | PNP | dRVVT | aβ2-IgG | aβ2-IgM | aβ2-IgA | aCL-IgG | aCL-IgM | aCL-IgA | All tests |
---|---|---|---|---|---|---|---|---|---|---|
Stoke+ TEST+ | 51 | 22 | 18 | 8 | 6 | 10 | 15 | 13 | 5 | 37 |
Stoke+ TEST− | 45 | 37 | 75 | 89 | 91 | 78 | 86 | 87 | 82 | 12 |
Stroke− TEST+ | 395 | 78 | 96 | 43 | 57 | 47 | 81 | 123 | 41 | 215 |
Stroke-−TEST− | 777 | 536 | 1179 | 1285 | 1271 | 1110 | 1298 | 1245 | 1089 | 236 |
p value | <0.0001 | <0.0001 | <0.0001 | NS | NS | 0.0016 | 0.0004 | NS | NS | 0.0002 |
Sensitivity (%) | 53 | 37 | 19 | 8 | 6 | 11 | 15 | 13 | 6 | 76 |
*p value vs | HPPNA | NS | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.009 |
PPV (%) | 11 | 22 | 16 | 16 | 10 | 18 | 16 | 10 | 11 | 15 |
Specificity (%) | 66 | 87 | 92 | 97 | 96 | 96 | 94 | 91 | 96 | 52 |
*p value vs | HPPNA | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
NPV (%) | 95 | 94 | 94 | 94 | 93 | 93 | 94 | 93 | 93 | 95 |
p values assessing differences in sensitivity and specificity are compared to HPPNA as a point of reference.