Table 8.
Body weight summary
| Average body weight (kg) | |||||
|---|---|---|---|---|---|
| Phase of study | Week within phase | Treatmenta | |||
| Control | 1× | 3× | 10× | ||
| Acclimation | 1 | 609.5 | 535.5 | 534.2 | 547.9 |
| 2 | 599.8 | 532.5 | 524.5 | 552.7 | |
| 3 | 604.3 | 538.5 | 529.0 | 553.6 | |
| Phase average | 604.5 | 535.5 | 529.2 | 551.4 | |
| Dosing | 1 | 599.3 | 543.2 | 526.3 | 551.4 |
| 2 | 594.0 | 553.0 | 535.8 | 548.3 | |
| 3 | 592.5 | 556.3 | 538.8 | 554.0 | |
| 4 | 576.5 | 547.3 | 526.8 | 541.3 | |
| Phase average | 590.6 | 550.0 | 532.0 | 548.8 | |
| Depuration | 1 | 636.5b | — | — | 553.2 |
| 2 | 643.5b | — | — | 548.5 | |
| Phase average | 640.0b | — | — | 544.4 | |
aTreatments correspond to target NBPT doses as follows: Control = 0 mg NBPT per kg BW; 1× = 1 mg NBPT per kg BW; 3× = 3 mg NBPT per kg BW; 10× = 10 mg NBPT per kg BW. Target dose values calculated based on the average BW of the dose group from the previously completed week.
bThis value represents a single animal that averaged 647.9 kg BW during the dosing phase.