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. 2019 Feb 26;3(2):842–854. doi: 10.1093/tas/txz023

Table 3.

The effects of encapsulated zinc butyrate (E-ZnB) supplementation on in vivo intestinal integrity before and after HS

Thermal neutral Control diet1 E-ZnB diet1,2 SEM P value
 Urine mannitol, ppm 904 1,001 166 0.684
 Urine lactulose, ppm 141 206 39 0.250
 Mannitol recovery, % 0.242 0.257 0.03 0.723
 Lactulose recovery, % 0.004 0.004 0.001 0.864
 Lactulose:mannitol ratio 0.017 0.019 0.004 0.678
HS
 Urine mannitol, ppm 646 648 119 0.990
 Urine lactulose, ppm 183 137 20 0.121
 Mannitol recovery, % 0.251 0.203 0.03 0.291
 Lactulose recovery, % 0.007 0.005 0.001 0.165
 Lactulose:mannitol ratio 0.030 0.024 0.004 0.278

1In vivo intestinal integrity was measured by gavaging the pigs with lactulose and mannitol through cookie dough and analyzing the urine before the hear stress was initiated and at the end of the HS (n = 6).

2Pigs were supplemented with 7.5 kg E-ZnB/MT of feed for 24 d and exposed to biphasic HS for 7 d.