Fig. 4. Chronological changes in quality of life (EORTC QLQ-STO22). EORTC, European Organisation for the Research and Treatment of Cancer; XDG, dysphagia; Xpain, pain; XRflx, reflux symptoms; XEatR, eating restrictions; Anx, anxiety; DM, having a dry mouth; T, taste; BI, body image; HL, hair loss. ^*Significant changes between the groups and over time.