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. 2020 Apr 25;17:894–903. doi: 10.1016/j.omtm.2020.04.014

Figure 6.

Figure 6

Intravitreal Delivery of scAAV2-C3 Reduced the Loss of RGCs after I/R Injury

(A) Representative images of Brn-3a immunofluorescence in the scAAV2-C3, scAAV2-C3 + I/R, scAAV2-EGFP, and scAAV2-EGFP + I/R groups. Brn-3a immunofluorescence was only detected in the GCL of the four groups. Blue, DAPI; red, Brn-3a-positive cell. (B) Quantitative analysis of Brn-3a-positive cells in the GCL per 300 μm of retina length. ∗p < 0.05 by an LSD post hoc test (n = 4); †p < 0.05 versus the scAAV2-EGFP + I/R group by an LSD post hoc test (n = 4). No statistical difference (p < 0.05) was detected by an LSD post hoc test between the scAAV2-C3 and the scAAV2-EGFP groups (n = 4). Error bars show SEM.