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. 2020 Apr 21;17:306–319. doi: 10.1016/j.omto.2020.04.007

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Silencing of DNMT3B Enhances Radiosensitivity via Promoting Superior Apoptosis in NPC Cells

(A) Apoptotic rates determined by flow cytometry. Compared to control groups, the apoptotic rate significantly increased in the DNMT3B-knockdown group after irradiation. (B and D) Representative images from colony formation assays in transfected NPC cells after irradiation (B, CNE2 cells; D, HNE1 cells). (C and E) Survival fraction curves of clone formation assays in transfected NPC cells with radiation (C, CNE2 cells; E, HNE1 cells). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.