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. 2020 Mar 20;48(2):479–497. doi: 10.1042/BST20190535

Table 2. Recently reported structures of small molecule inhibitors of E3 ligases.

Target Compound ID Structure Reference
TRAF6 1, C25-140 graphic file with name BST-48-479-g0024.jpg Brenke et al. [62]
RNF4 2, TRH 1-23 graphic file with name BST-48-479-g0025.jpg Ward et al. [63]
3, CCW16 graphic file with name BST-48-479-g0026.jpg
VHL 4a: X = F, Z = H
4b: X = H, Z = F
graphic file with name BST-48-479-g0027.jpg Testa et al. [64]
WWP2 5 graphic file with name BST-48-479-g0028.jpg Watt et al. [65]
6 graphic file with name BST-48-479-g0029.jpg
7 graphic file with name BST-48-479-g0030.jpg
8 graphic file with name BST-48-479-g0031.jpg
9 graphic file with name BST-48-479-g0032.jpg
SMURF1 10, HS-152 graphic file with name BST-48-479-g0033.jpg Tian et al. [66]
HOIP 11, Bendamustine graphic file with name BST-48-479-g0034.jpg De Cesare et al. [67]
12 graphic file with name BST-48-479-g0035.jpg Johansson et al. [68]
13 graphic file with name BST-48-479-g0036.jpg
14 graphic file with name BST-48-479-g0037.jpg