Table 2.
Biochemical and dialysis-related parameters according to the presence or absence of vitamin D deficiency.
| Variable | All patients | Normal | Vitamin D-deficient | p value |
|---|---|---|---|---|
| N = 186 | N = 117 | N = 69 | ||
| BUN (mg/dL) | 70 ± 22 | 72 ± 24 | 67 ± 19 | 0.20 |
| Creatinine (mg/dL) | 11 ± 3 | 11 ± 3 | 10 ± 3 | 0.045* |
| Hemoglobin (g/dL) | 10 ± 1 | 11 ± 1 | 10 ± 2 | 0.12 |
| Albumin (g/dL) | 3.8 ± 0.4 | 3.8 ± 0.4 | 3.7 ± 0.4 | 0.12 |
| hs-CRP (mg/L) | 10 ± 19 | 8 ± 14 | 10 ± 22 | 0.62 |
| Calcium (mg/dL) | 9 ± 1 | 9 ± 1 | 9 ± 1 | 0.86 |
| Phosphate (mg/dL) | 5.2 ± 1.8 | 5.1 ± 1.6 | 5.2 ± 1.7 | 0.80 |
| Cholesterol (mg/dL) | 180 ± 49 | 180 ± 50 | 170 ± 50 | 0.28 |
| $Ca × P, mg2/dL2 | 49 ± 17 | 48 ± 17 | 49 ± 18 | 0.72 |
| i-PTH (pg/mL) | 360 ± 380 | 330 ± 330 | 450 ± 860 | 0.16 |
| IL-1 beta (pg/mL) | 1.8 ± 5.7 | 2.0 ± 7.4 | 1.5 ± 1.1 | 0.60 |
| IL-6 (pg/mL) | 6.5 ± 29.5 | 8.3 ± 38.8 | 3.9 ± 4.4 | 0.46 |
| TNF-alpha (pg/mL) | 17 ± 68 | 17 ± 65 | 19 ± 78 | 0.92 |
| 25(OH) Vitamin D (ng/mL) | 27 ± 15 | 35 ± 14 | 14 ± 4 | <0.001* |
| Kt/V | 1.7 ± 0.4 | 1.7 ± 0.3 | 1.6 ± 0.4 | 0.17 |
| URR (%) | 0.7 ± 0.1 | 0.8 ± 0.1 | 0.7 ± 0.1 | 0.17 |
*p value <0.05.
Statistical significance based on t-test for continuous variables.
Abbreviations: BUN, blood urea nitrogen; hs-CRP, high-sensitivity C-reactive protein; i-PTH, intact parathyroid hormone; IL-1 beta, interleukin 1 beta; IL-6, interleukin 6; TNF-alpha, tumor necrosis factor-alpha; URR, urea reduction rate.
$Product of serum calcium and phosphate.