Table 2.
Age, subfield volume or activation predicting LDI-performance.
Volume and Age associations with LDI | Activation and Age associations with LDI | |||||||
---|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | |||
Volume | Age smooth | Volume smooth x Age smooth | Volume x Age smooth | Activation | Age smooth | Activation smooth x Age smooth | Activation x smooth Age | |
Left CA1 | 0.70 | 7.77*** | 1.28 | 1.71 | 2.47* | 17.56*** | 0.35 | 0.16 |
Right CA1 | 0.33 | 7.35*** | 0.95 | 1.54 | 2.60* | 19.43*** | 0.98 | 0.61 |
Left CA3 | 1.01 | 8.09*** | 1.13 | 1.24 | 0.09 | 7.06*** | 2.64*∆ | 2.73* |
Right CA3 | 0.99 | 7.33*** | 2.58 | 1.97 | 1.74 | 8.26*** | 3.34**∆ | 1.17 |
Left DG | 1.43 | 8.21*** | 2.07*∆ | 2.34 | 1.20 | 8.11*** | 1.75 | 1.55 |
Right DG | 0.34 | 7.34*** | 3.32*∆ | 1.58 | 1.77 | 16.81*** | 0.84 | 0.46 |
Note: Reported values are F-values. Covariates included in all generalized additive models are sex and education. Age is added as smooth variable in all models. Volume and activation are explored as smooth and linear terms. In models 1 the main effects (without the interaction in the model) are reported, for models 2 and 3 only the interactions are reported. More detailed statistical information is provided in Supplementary Tables 1 and 2. *Indicates significance (* p < 0.05; **p < 0.01; ***p < 0.001). ∆ indicates best model fit.