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. 2020 May 5;10:7598. doi: 10.1038/s41598-020-64564-6

Table 3.

Multivariable Cox proportional hazards regression.

adjusted HR (95% CI) p value
Model A
Subtype
Luminal A Reference
Luminal B 1.46 (0.54–3.95) 0.462
Her2 + 0.87 (0.19–4.01) 0.856
TNC 1.57 (0.47–5.22) 0.46
pTNM
0 0.51 (0.03–9.79) 0.652
I 1.23 (0.46–3.28) 0.673
II Reference
III 3.63 (1.53–8.58) 0.003
IV 7.89 (1.79–34.68) 0.006
Model B
Subtype
Luminal A Reference
Luminal B 1.40 (0.51–3.83) 0.518
Her2 + 0.57 (0.12–2.71) 0.476
TNC 1.43 (0.42–4.85) 0.566
pTNM
0 1.96 (0.10–38.63) 0.658
I 1.56 (0.08–30.19) 0.768
II Reference
III 5.46 (0.29–104.18) 0.259
IV 9.28 (0.37–231.50) 0.175
Rim enhancement
No Reference
Yes 1.58 (0.74–3.38) 0.234
Ipsilateral vascularity
<3 Reference
≥3 2.67 (1.28–5.60) 0.009
Model C
Subtype
Luminal A Reference
Luminal B 1.84(0.66–5.15) 0.246
Her2 + 0.81(0.17–3.80) 0.787
TNC 2.56(0.73–8.98) 0.141
pTNM
0 0.58(0.03–11.53) 0.723
I 1.45(0.53–3.96) 0.470
II Reference
III 3.59(1.44–9.00) 0.006
IV 3.86(0.79–18.85) 0.095
Texture analysis: Skewness
<0.29 Reference
≥0.29 2.85(1.17–6.94) 0.021
Kep: 25perc
<0.20 Reference
≥0.20 3.84(1.16–12.72) 0.028
Model D
Subtype
Luminal A Reference
Luminal B 1.71 (0.60–4.88) 0.317
Her2 + 0.53 (0.11–2.61) 0.437
TNC 1.96 (0.54–7.06) 0.306
pTNM
0 0.85 (0.04–16.96) 0.913
I 1.46 (0.53–4.05) 0.465
II Reference
III 3.45 (1.37–8.67) 0.008
IV 3.27 (0.67–16.00) 0.144
Rim enhancement
No Reference
Yes 2.09 (0.92–4.76) 0.08
Ipsilateral vascularity
<3 Reference
≥3 2.71 (1.25–5.86) 0.011
Texture analysis: Skewness
<0.29 Reference
≥0.29 3.21 (1.26–8.23) 0.015
Kep: 25perc
<0.20 Reference
≥0.20 2.66 (0.82–8.67) 0.105