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. 2020 May 5;10:7507. doi: 10.1038/s41598-020-64558-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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ROC curves for Tetranectin (a), BNP (b), and a comparison of Tetranectin and BNP (c) differentiating between patients without and with HF (study cohort 1, n = 100). Circulating Tetranectin and BNP were measured using ELISA and Triage Meter Point of care assay, respectively. Specificity and sensitivity thresholds, and area under the curve (AUC) with 95% Confidence Intervals presented. Correlation between Tetranectin and BNP is highlighted (d). Correlation coefficient was assessed using Pearson method.