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. 2020 Apr 22;43:100789. doi: 10.1016/j.dcn.2020.100789

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 5 — Effect of 2-week withdrawal from cocaine exposure during adolescence on total BDNF mRNA levels in the PrhC.

Rats were treated with cocaine or saline from PND 28 to PND 42. Two weeks after the end of treatment (PND 56), rats were tested for NOR and sacrificed immediately after the test.

Results are expressed as percentages of saline-treated rats not exposed to NOR (saline-no test). Histograms represent the mean ± SEM of six to seven rats per group. *p < 0.05, ***p < 0.001 vs. saline-no test rats; ^###p < 0.001 vs. cocaine-no test (two-way ANOVA followed by Tukey HSD test).