Figure 10.

A Comparison of the Genes Included in the Different State Metrics across Cancers

(A) Venn diagram illustrating overlap in genes contained in the opposing state metrics for terminally differentiated/epithelial versus de-differentiated/mesenchymal extracted from breast cancer (blue circle) and melanoma (red circle) cell lines. The subset of the genes listed below the Venn diagram were annotated with transcription factor GO terms.

(B) A biplot of the Ki values for the overlapping genes in the terminally differentiated/epithelial state metrics (blue circles and blue linear trendline) and in the de-differentiated/mesenchymal state metrics (orange circles and orange linear trendline). A 1:1 correspondence is represented by the black dotted line.