Table 2.
HPLC Determination of Ranolazine (RAN) Plasma Concentrations 12 h after i.p. Administration of Ranolazine at 25, 50, or 100 mg/kg
| RAN Dose (mg/kg) | WT (μM) | SOD1G93A (μM) |
|---|---|---|
| 25 | 0.63 ± 0.16 | 0.79 ± 0.11 |
| 50 | 1.22 ± 0.20 | 1.30 ± 0.18 |
| 100 | 3.33 ± 0.21 | 2.87 ± 0.17 |
Data are expressed as mean ± SD, n = 5 per group.