Table 1.
DDR gene panel.
| BER | CPF | FA | HRR | MMR | NER | NHEJ | TLS |
|---|---|---|---|---|---|---|---|
| MUTYH | ATM | BLM | BRCA1 | MLH1 | ERCC1 | MRE11A | POLH |
| POLD1 | ATR | BRIP1 | BRCA2 | MLH3 | ERCC2 | PRKDC | |
| POLE | CHEK1 | FANCA | NBN | MSH2 | ERCC3 | ||
| PARP1 | CHEK2 | FANCC | RAD50 | MSH6 | ERCC4 | ||
| PARP2 | PALB2 | RAD51 | PMS1 | ||||
| RAD51C | RAD51B | PMS2 | |||||
| RAD51D | |||||||
| RAD54L | |||||||
| RECQL4 | |||||||
| WRN |
BER, base excision repair; CPF, check point factor; FA, Fanconi anemia; HRR, homologous recombination repair; MMR, mismatch repair; NER, nucleotide excision repair; NHEJ, nonhomologous end-joining; TLS, DNA translesion synthesis.