Table 1.
Clinical and microbial characteristics of 55 French patients with menstrual toxic shock syndrome (2011–2017).
| Characteristics | MTSS, n = 55 (%) |
|---|---|
| Age in years, median ± IQR | 17.9 (16.0–21.7) |
| Comorbidity | 0 (0) |
| Hospitalization in an intensive care unit | 47 (85) |
| CDC diagnostic criteria* | |
| Confirmed cases | 30 (55) |
| Probable cases | 25 (45) |
| Fever (≥39°C) | 55 (100) |
| Hypotension or | 55 (100) |
| Rash§ | 52/54 (96) |
| Desquamation§ | 37/48 (77) |
| ≥3/7 Organ involvement§ | 45/55 (100) |
| Digestive§ | 45/55 (82) |
| Muscular§ | 33/49 (67) |
| Mucosal§ | 38/52 (73) |
| Renal§ | 30/54 (55) |
| Hepatic§ | 30/52 (58) |
| Hematologic§ | 17/52 (33) |
| Neurologic§ | 7/50 (14) |
| Mortality | 0 (0) |
| Characteristics of S. aureus vaginal isolate, n (%) | |
| CC6, tst+, mecA− | 1 (2) |
| CC8, tst+, mecA− | 1 (2) |
| CC30, tst+, mecA− | 52 (94) |
| CC45, tst+, mecA− | 1 (2) |
CC denotes clonal complex, tst+ presence of tst gene coding for TSST-1, mecA− absence of mecA gene, IQR interquartile range, and MTSS menstrual toxic shock syndrome.
⁎
Definition of probable or confirmed TSS cases was base on CDC definition [26] with 5 criteria: fever, hypotension rash, late desquamation, and minimum of 3/7 organ involvements. TSS cases were confirmed when 5/5 criteria were present, and probable it was only 4/5 criteria.
§
n/total (%).