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. 2020 Apr 30;14:1651–1662. doi: 10.2147/DDDT.S249162

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© 2020 Wang et al.

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Effect of AST on P2X7R, IL-1β, Cox-2 and TNF-α expression in rats. (A) The protein P2X7R, TNF-a, IL-1β and Cox-2 levels in cortex and hippocampus. (B) The relative protein levels of P2X7R, TNF-α, IL-1β and Cox-2 in hippocampus. (C) The relative protein levels of P2X7R, TNF-α, IL-1β and Cox-2 in cortex. (D) The relative mRNAs levels of P2X7R, TNF-α, Cox-2 and IL-1β in the hippocampus. (E) The relative mRNAs levels of P2X7R, TNF-α, IL-1β and Cox-2 in the cortex. (F) Pearson correlation analysis of mRNA expression of P2X7R and IL-1β RNA in hippocampus of SE group. The relative expression of protein and mRNA were normalized to β-actin expression. Values are presented as the mean ± SD (n=5, *p < 0.05, **p < 0.01vs. Control; ^#p < 0.05, ^##p < 0.01vs. SE).