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BJE restrained autophagy in the MDA-MB-231-xenograft murine breast cancer model. (A) Protein expressions of LC 3 II/I, p62, Beclin-1, and ULK1 in tumor tissue. (B) Phosphorylation of mTOR, Akt, and PI3K in tumor tissue. (C) mRNA levels of LC 3, ATG13 and ATG5 in tumor tissue. n=5–6, data was presented as mean ± SD. *p < 0.05 and **p < 0.01 vs. Model group.
