Skip to main content
. 2020 Mar 31;24(1):31–41. doi: 10.12717/DR.2020.24.1.31

Table 2. Effects of endoplasmic reticulum stress inhibitor and antioxidant treatments during micromanipulation on the in vitro development of somatic cell nuclear transfer embryos.

Treatment No. of embryos cultured No. of embryos developed to Cell no. in blastocysts (mean±SE)
≥2-Cell (%) Blastocyst (%)
Control 265 173 (65.3)a 39 (14.7)a 46.2±2.6a
TUD 222 161 (72.5)ab 55 (24.8)b 63.5±3.3b
Vit. C 241 175 (72.6)ab 53 (22.0)b 60.2±4.1b
TUD+Vit. C 245 182 (74.3)b 47 (19.2)ab 59.7±4.3b

Experiments were repeated 6 times in each treatment group.

a,b

Values with different superscripts are significantly different (p<0.05).

TUD, 100 μM TUDCA (tauroursodeoxycholic acid); Vit. C, 100 μM vitamin C.