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3′UTR shortening is associated to ER-'s aggressive phenotypes in ceRNA. (A) Intersection of 3′US ceRNA partners between ER- and ER+ normal ceRNA networks. (B) IPA canonical pathways significantly (P < 0.01) enriched for the ER- 3′US ceRNAs. The pathways are color-coded by keyword: “cancer” in blue, “signaling” in red, and those associated with aggressive phenotypes (Krishnan et al., 2013) in green. (C) Intersection of 3′US ceRNA partners in ER- between normal and tumor ceRNA networks.
