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The experimental (red dots) and modeling (blue line) results for the growth of (A) cells and (B) ECM volume over 28 days of culture. The amount of cells was experimentally estimated based on DNA quantification (Sonnaert et al., 2017). Results are shown as mean ± standard deviation. The ECM volume was measured by contrast-enhance nanofocus CT imaging (Papantoniou et al., 2014b).
