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. 2020 Apr 29;20:385–399. doi: 10.1016/j.omtn.2020.01.026

Figure 8.

Figure 8

The Schematic Diagram Depicts the Regulatory Mechanism of circ_001653 in the Proliferation, Apoptosis, and ECM Synthesis of NPCs

Loss of circ_001653 allows expression of miR-486-3p in NP tissues and NPCs. CEMIP downregulation may promote NPC proliferation and inhibit its apoptosis, contributing to the ECM synthesis.