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. 2020 Apr 28;26(16):1912–1925. doi: 10.3748/wjg.v26.i16.1912

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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Local gene expression of Foxp3, IL-10; IL-23A; TGFB1; IL-6 and IL-17A in inflammatory bowel disease patients and in early and advanced colorectal cancer cases. A: Foxp3; B: IL-10; C: IL-23A; D: TGFB1; E: IL-6; F: IL-17A. The relative quantity of target mRNAs in inflamed and tumoral tissue is calibrated to their normal counterparts after normalization to endogenous control–18S rRNA. The results are presented as mean (line) with standard error (box), and standard deviation (whiskers) of log-transformed fold changes (base 10). IBD: Inflammatory bowel disease; CRC: Colorectal cancer.