Table 5.

Serum levels of anti and pro-inflammatory cytokines in inflammatory bowel disease patients compared to early and advanced colorectal cancer cases

Cytokines	IBD	Early CRC	P value (U-test), IBD vs early CRC	Advanced CRC	P value (U-test), IBD vs advanced CRC
TGFB1 (ng/mL)	11.19 (9.36-20.99)	22.74 (18.17-27.98)	0.001344	21.51 (15.5-31.05)	0.0031
IL-10 (pg/mL)	0.4 (0.0-2.8)	7.73 (6.0-12.71)	0.000006	8.84 (7.2-19.81)	0.000002
IL-6 (pg/mL)	0.0 (0.0-2.7)	3.06 (2.03-4.19)	0.0153	4.19 (2.15-8.4)	0.044
IL-23A (pg/mL)	0.7 (0.0-3.7)	25.7 (24.6-32.5)	0.000024	30.5 (26.3-33.5)	0.000009
IL-17A (pg/mL)	0.0 (0.0-0.26)	3.62 (0.0-8.23)	0.0086	1.2 (0.0-12.08)	0.178

The results are presented as median (IQR, 25%-75% percentile). IBD: Inflammatory bowel disease; CRC: Colorectal cancer.