. 2020 Apr 18;23(5):101072. doi: 10.1016/j.isci.2020.101072

Table 1.

Condition Optimization


Entry	Vary from Optimized Condition	Yield^a	Major By-products
1	None	78%–83%
2	Without HOAc	<50% conversion for 3 days
3	Without Na₂WO₄-2H₂O	Trace^b
4	H₃O₄₀PW₁₂-xH₂O instead of Na₂WO₄-2H₂O	64%^c
5	(NH₄)₁₀(H₂W₁₂O₄₂)-xH₂O instead of Na₂WO₄-2H₂O	77%^c
6	LiBr instead of NaBr	66%^d
7	KBr instead of NaBr	75%^d
8	SPB instead of H₂O₂	N.R
9	MeOH instead of EtOH	67%
10	H₂O instead of EtOH	67%
11	Na₂WO₄-2H₂O, 1 mol % instead of 5 mol %	67%
12	2.0 equiv H₂O₂ instead of 6.0 equiv	57%

N.R, no reaction

All the reactions were conducted in 1.0-mmol scale (1-1) for 12 h, isolated yield.

2.0 equivalents of HOAc was utilized.

1.5 equivalents NaBr and 2.0 equiv. HOAc were utilized.

1.5 equivalents of NaBr and 2.0 equivalents of HOAc were utilized, and the reactions were conducted at 50°C