Table 1. Characteristics of All Patients Tested for SARS-CoV-2 and Patients Who Tested Positive by ACEI and ARB Use.
| Characteristic | No. (%) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All patients tested for SARS-CoV-2 (n = 18 472) | Patients who tested positive for SARS-CoV-2 (n = 1735) | |||||||||||
| ACEI | P value | ARB | P value | ACEI | P value | ARB | P value | |||||
| Yes | No | Yes | No | Yes | No | Yes | No | |||||
| Total | 1322 (7) | 17 150 (93) | NA | 982 (5) | 17 490 (95) | NA | 116 (7) | 1619 (93) | NA | 98 (6) | 1637 (94) | NA |
| Age, mean (SD), y | 62 (16) | 48 (21) | <.001 | 65 (14) | 48 (21) | <.001 | 63 (15) | 53 (19) | <.001 | 65 (13) | 53 (19) | <.001 |
| Male | 699 (53) | 6685 (39) | <.001 | 437 (45) | 6947 (40) | .003 | 67 (58) | 792 (49) | .08 | 58 (59) | 801 (49) | .06 |
| White | 955 (72) | 11 770 (69) | <.001 | 665 (68) | 12 060 (69) | <.001 | 57 (49) | 1038 (65) | <.001 | 59 (60) | 1036 (64) | .15 |
| Black | 284 (22) | 3342 (20) | 255 (26) | 3371 (19) | 50 (43) | 369 (23) | 31 (32) | 388 (24) | ||||
| Othera | 81 (6) | 1952 (11) | 61 (6) | 1972 (11) | 9 (8) | 201 (13) | 8 (8) | 202 (12) | ||||
| BMI, >30b | 613 (54) | 4306 (41) | <.001 | 480 (55) | 4439 (41) | <.001 | 60 (59) | 399 (45) | .01 | 48 (60) | 411 (46) | .02 |
| Diabetes | 626 (48) | 2852 (17) | <.001 | 484 (50) | 2994 (17) | <.001 | 63 (54) | 269 (17) | <.001 | 48 (50) | 284 (18) | <.001 |
| CAD | 380 (29) | 1799 (11) | <.001 | 331 (34) | 1848 (11) | <.001 | 24 (21) | 137 (9) | <.001 | 23 (24) | 138 (9) | <.001 |
| Hypertension | 1235 (94) | 6077 (36) | <.001 | 939 (96) | 6373 (37) | <.001 | 112 (97) | 570 (37) | <.001 | 90 (93) | 592 (38) | <.001 |
| COPD | 301 (23) | 1885 (11) | <.001 | 244 (25) | 1942 (11) | <.001 | 13 (11) | 101 (6) | .06 | 16 (16) | 98 (6) | <.001 |
| HF | 329 (25) | 1550 (9) | <.001 | 305 (32) | 1574 (9) | <.001 | 16 (14) | 130 (8) | .07 | 19 (20) | 127 (8) | <.001 |
Abbreviations: ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; HF, heart failure; NA, not applicable; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
a
The other category included Asian, American Indian/Alaska Native, Hispanic American, Native Hawaiian/other Pacific Islander, multiracial, other, or prefer not to answer
b
BMI data were available for 11 780 patients.