Table 4.
Crude and Adjusted Odds Ratios From Logistic Regression Analysis for the Association Between Serogroup, Case Characteristics, Clinical Manifestation, and Death Among Invasive Meningococcal Disease Cases, the Netherlands, January 2015 to June 2018
| Crude | Adjusted | |||
|---|---|---|---|---|
| Variables | OR (95% CI) | P | OR (95% CI) | P |
| Serogroup | ||||
| Non-Wa | Reference | |||
| W | 4.2 (2.3–8.2) | <.001 | 4.3 (2.0–10.2) | <.001 |
| Age | ||||
| 0–9 y | Reference | |||
| 10–19 y | 2.8 (1.0–8.4) | .052 | 1.4 (.4–4.9) | .551 |
| 20–64 y | 2.3 (.9–6.4) | .093 | 0.8 (.3–2.7) | .729 |
| ≥65 y | 1.7 (.7–5.1) | .283 | 0.4 (.1–1.6) | .197 |
| Gender | ||||
| Male | Reference | |||
| Female | 1.0 (.5–1.8) | .910 | 0.9 (.4–2.1) | .878 |
| Comorbidities | ||||
| No | Reference | |||
| Yes, immunocompromised | 2.4 (.9–5.8) | .055 | 2.5 (.8–7.5) | .114 |
| Yes, other | 0.9 (.3–2.4) | .811 | 1.3 (.3–4.2) | .685 |
| Clinical manifestations | ||||
| Meningitis without septicemia | Reference | |||
| Septicemia without meningitis | 14.3 (5.0–61) | <.001 | 9.3 (3.0–41) | <.001 |
| Septicemia and meningitis | 14.1 (3.9–67) | <.001 | 11.3 (2.8–57) | .001 |
| Other | 2.1 (.5–11) | .325 | 1.1 (.2–6.1) | .952 |
For 2018 only until June 2018.
Abbreviations: CI, confidence interval; IMD, invasive meningococcal disease; OR, odds ratio.
aNon-W includes cases of serogroup B, Y, and C.