Table 2.
Clinical Features of Patients With Parapertussis, by Age—Wisconsin, 1 October 2011–31 May 2012
| Clinical Feature | All Ages No. (%)a (n = 218) | Aged <1 y No. (%)a (n = 25) | Aged 1–4 y No. (%)a (n = 69) | Aged 5–9 y No. (%)a (n = 93) | Aged ≥10 y No. (%)a (n = 31) | P Valueb |
|---|---|---|---|---|---|---|
| Cough | 218 (100) | 25 (100) | 69 (100) | 93 (100) | 31 (100) | … |
| Cough duration (days), median (IQR) | 15 (10–26) | 15 (10–27) | 16 (9–28) | 15 (10–26) | 15 (10–24) | .527 |
| Paroxysmal cough | 131 (60) | 14 (56) | 47 (68) | 53 (57) | 17 (55) | .931 |
| Paroxysmal cough duration (days), median (IQR) | 7 (4–11) | 5 (3–8) | 7 (5–9) | 7 (3–12) | 8 (6–12) | .074 |
| Posttussive vomiting | 67 (31) | 11 (44) | 23 (33) | 28 (30) | 5 (16) | .035c |
| Whoop | 33 (15) | 5 (20) | 11 (16) | 11 (12) | 6 (19) | 1.000 |
| Apnea | 19 (9) | 4 (16) | 9 (13) | 4 (4) | 2 (6) | .047c |
| Sleep disturbance in patient | 154 (71) | 19 (76) | 52 (75) | 65 (70) | 18 (58) | .208 |
| Sleep disturbance in any household memberd | 106 (55) | 13 (57) | 39 (64) | 39 (48) | 15 (54) | .833 |
| Cyanosisd | 2 (1) | 1 (4) | 1 (2) | 0 (0) | 0 (0) | .462 |
| Feverd | 51 (25) | 10 (43) | 16 (24) | 19 (22) | 6 (20) | .079 |
| Weight lossd | 15 (8) | 1 (4) | 5 (9) | 7 (9) | 2 (7) | 1.000 |
| Hospitalized | 2 (1) | 2 (8) | 0 (0) | 0 (0) | 0 (0) | .184 |
| Met pertussis clinical case definitione | 103 (47) | 9 (36) | 36 (52) | 46 (49) | 12 (39) | .835 |
| Received recommended antibioticf | 194 (89) | 22 (88) | 61 (88) | 82 (88) | 29 (94) | .579 |
| Days from cough onset to antibiotic receipt, median (IQR) | 7 (4–13) | 7 (4–15) | 7 (4–11) | 6 (3–12) | 7 (3–14) | .677 |
Abbreviation: IQR, interquartile range.
All data are presented as number and percentage except for the cough and paroxysmal cough durations, which are presented as median and IQR.
Difference among patients aged <1 year and patients aged ≥10 years were calculated using χ2 or Fisher exact test for differences in categorical variables or Mann–Whitney U test for differences in continuous variables.
P-value of Cochran–Armitage test for trend with age.
Percentages exclude patients with missing information.
Illnesses were classified by whether they met the Council of State and Territorial Epidemiologists clinical case definition of pertussis (cough illness ≥14 days with ≥1 of the following: whoop, paroxysms, or posttussive vomiting) used during 2011–2012 [25].
Recommended antibiotic treatment includes azithromycin, erythromycin, clarithromycin, or trimethoprim-sulfamethoxazole.