Table 3.

Gene expression associates with clinical outcomes.

Gene expression	P value	Association with clinical outcome	Pathways involved with IBD
↑ IRGM	P = 0.001	Medical treatment response to aminosalicylates (5-ASAs)	Autophagy
↑ FOXO4	P = 0.05	Histological remission	Immune response
↑ CTLA4	P = 0.05	Histological activity index score
↓ SLC26A3	P = 0.001	Clinical course: the course of the same initial activity and prolonged remission	Solute transport
↑ SLC39A4	P = 0.0007	Evolution: tendency to years of evolution of between 10 and 15 years
↑ SOD2	P = 0.00004	Severe histological activity	Oxidative stress
↑ TDO2	P = 0.06	Clinical course: characterized by the presence of initial activity and then prolonged remission more than 5 years
↑ ALDOB	P = 0.005	Evolution: early age at diagnosis of less than 40 years	Carbohydrate metabolism
↑ ALDOB	P = 0.005	Clinical course: prolonged benign clinical course characterized by the presence of higher initial activity and remission at 5 years