Table 2.
Univariate and multivariate Cox regression analyses of risk factors for overall survival rate (n = 337).
| Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| OS (%) | HR | 95% CI | P value | HR | 95% CI | P value | ||
| Age | <50 (n = 125) | 87 (69.6%) | 1.060 | 0.714–1.573 | 0.773 | |||
| ≥50 (n = 212) | 142 (67.0%) | |||||||
|
| ||||||||
| Gender | Female (n = 75) | 53 (70.7%) | 1.231 | 0.770-1.967 | 0.385 | |||
| Male (n = 262) | 176 (67.2%) | |||||||
|
| ||||||||
| Liver cirrhosis | Absent (n = 25) | 15 (60%) | 1.420 | 0.740-2.722 | 0.291 | |||
| Present (n = 312) | 214 (68.6%) | |||||||
|
| ||||||||
| AFP | <20 (n = 164) | 118 (72.0%) | 1.269 | 0.866-1.860 | 0.222 | |||
| ≥20 (n = 173) | 111 (64.2%) | |||||||
|
| ||||||||
| Tumor multiplicity | Single (n = 258) | 174 (67.4%) | 1.095 | 0.916-1.209 | 0.696 | |||
| Multiple (n = 79) | 55 (69.6%) | |||||||
|
| ||||||||
| Maximal tumor size | <5 cm (n = 190) | 127 (66.8%) | 1.063 | 0.638-1.174 | 0.756 | |||
| ≥5 cm (n = 147) | 102 (69.4%) | |||||||
|
| ||||||||
| Pathologic TNM stage | I/II (n = 265) | 196 (74.0%) | 3.136 | 2.112-4.658 | <0.001 | 3.161 | 2.129-4.695 | <0.001 |
| III/IV (n = 72) | 33 (45.8%) | |||||||
|
| ||||||||
| FEN1 level | Low (n = 173) | 126 (72.8%) | 1.881 | 1.066-2.285 | 0.022 | 1.585 | 1.083-2.320 | 0.018 |
| High (n = 164) | 103 (62.8%) | |||||||