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. 2020 Jan 13;2020:2460158. doi: 10.1155/2020/2460158

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Copyright © 2020 Wenbin Lu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Conversion of Ly6C^high to Ly6C^low monocytes when cocultured with MSCs. (a) After stimulation with LPS (1 μg/ml), monocytes were cocultured with or without MSCs (control). Ly6C^low monocytes at day 1 and day 3 were then determined by FACS. (b) Expression levels of NR4A1 in two groups of Ly6C^high/low monocytes (corresponding to (a)) were then tested. ^∗p < 0.05 at day 3 vs. the first day. Abbreviations: FITC: fluorescein isothiocyanate; MSCs: mesenchymal stem cells; PE: phycoerythrin; NR4A1: nuclear receptor subfamily 4 group A member 1.