Figure 4.

Myocardial remodeling and apoptosis of cardiac myocytes under different levels of NR4A1. (a) Direct visualization of the lysis of myocardial fibrosis after myocardial infarction through Mason staining at day 1 and day 3. ^∗p < 0.05 vs. day 1, ^#p < 0.05 vs. the corresponding low-NR4A1 expression level group; (b) TUNEL⁺ cardiac myocytes at day 3 and day 7 were then separated in two groups as defined above. ^∗p < 0.05 vs. the corresponding low-NR4A1 expression level group. Abbreviations: NR4A1: nuclear receptor subfamily 4 group A member 1; TUNEL: terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling.