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. 2020 Jan 20;2020:9817095. doi: 10.1155/2020/9817095

Figure 5.

Figure 5

(a) Effect of resistin (100 ng/mL) on ALP activity in PDL fibroblasts after 1 day. ALP activity was significantly reduced in the presence of resistin (n = 3). (b) Effect of resistin (30, 100, and 300 ng/mL) on BMP2 mRNA expression in PDL fibroblasts after 1 day (n = 9). Effect of resistin (100 ng/mL) on hard tissue markers (BMP2, RUNX2, and OCN), matrix markers (POSTN and COL I), and growth factors (TGF-β and VEGF) involved in bone metabolism (n = 9) at 1 day (c) and 3 days (d). Results are expressed as the mean ± SD. All these molecular markers were downregulated in PDL fibroblasts after 1 and 3 days of incubation with resistin. ∗Significant difference (p < 0.05).