Table 3.
Reliability of serum markers in the definition of moderate fibrosis (F ≥ 2).
| NAFLD score | BARD score | FIB-4 | |
|---|---|---|---|
| Cut − off<−1.455 % (95% CI) |
Cut − off ≥ 2 % (95% CI) |
Cut − off > 0.41 % (95% CI) |
|
| Sensitivity | 30 (12-54) | 46 (27-67) | 68 (46-85) |
| Specificity | 89 (52-99) | 54 (27-79) | 67 (52-98) |
| Likelihood ratio + | 2.7 (1.3-5.5) | 0.6 (0.1-3) | 2 (1.3-3.2) |
| Likelihood ratio - | 0.8 (0.1-5.1) | 1.1 (0.84-1.34) | 0.5 (0.1-4.4) |
| Positive predictive value | 93 (82-97) | 50 (13-86) | 77 (45-92) |
| Negative predictive value | 22 (12-38) | 36 (31-42) | 55 (29-78) |
| Accuracy | 64.3 (48-78.5) | 37 (23-54) | 60 (42-74) |
| AUROC∗ | 0.53 | 0.5 | 0.7 |
∗The area under the receiver-operating characteristic.