Table 4.

ROC curve characteristics of plasma 8-hydroxy-2′-deoxyguanosine as a biomarker in POAG.

Characteristics	Value	95% confidence interval
Cutoff value, ng/mL	≥14.8	–
AUC (SE)	0.653 (0.057)	0.54 – 0.76
p value	0.010	–
Sensitivity, %	78.0	64.0 – 88.4
Specificity, %	53.3	37.8 – 68.3
Positive likelihood ratio	1.67	1.18 – 2.36
Negative likelihood ratio	0.41	0.23 – 0.74
Positive predictive value, %	65.0	56.8 – 72.4
Negative predictive value, %	68.5	54.7 – 79.7
Accuracy, %	66.3	55.9 – 75.7

AUC, area under the receiving operating characteristics curve; POAG, primary open-angle glaucoma; ROC, receiver operating characteristic.